7:45 am Registration and Continental Breakfast
Lobby of the Technology Institute Building, 2145 Sheridan Road, Evanston, IL 60208
8:15 am Welcome and Introductory Remarks
Program Chair: Michael McLeish, IUPUI
LR2 Tech Building
8:20 am First session (LR2 Tech Building)
Session Chair: Hazel Holden,University of Wisconsin-Madison
8:20 am Brian Smith, Medical College of Wisconsin
Nitric oxide synthase molecular architecture and domain interfaces regulate electron transfer and calmodulin activation
8:50 am Jennifer Fishovitz, University of Notre Dame
Triggering of allostery in penicillin-binding protein 2a of methicillin-resistant Staphylococcus aureus
9:20 am Morgan Milton, Iowa State University
X-ray crystallography and high-throughput screening to identify inhibitors of the Plasmodium falciparum apicoplast DNA polymerase
9:50 am Coffee Break
Lobby of Tech Building
10:15 am Second session (LR2 Tech Building)
Session Chair: Joe Kappock, Purdue University
10:15 am David Minh, Illinois Institute of Technology
Finding needles in haystacks: enzyme activity classification based on implicit ligand theory
10:45 am Tatiana Mishanina, University of Michigan
Unusual flavin derivative intermediate in FAD-dependent thymidylate synthase
11:15 pm Govardhan reddy Veerareddygari, University of Louisville
A primary 2′-deuterium kinetic isotope effect indicates that pseudouridine synthases proceed through a glycal intermediate
11:45 am James Vasta, University of Wisconsin-Madison
Selective and bioavailable inhibitors of collagen prolyl 4-hydroxylase
12:15 pm Lunch
Box lunch or on your own. For those who are interested, during the lunch break (~12:45 pm) Dr. Chi-Hao Luan (Northwestern University High Throughput Analysis Laboratory) will give a 30 minute presentation on:
The fluorescence thermal shift (FTS) assay and its application in protein sciences and drug discovery. The presentation will be in LR2 of the Tech Building.
1:30 pm Third session (LR2 Tech Building)
Session Chair: Rachel Powers, Grand Valley State University
1:30 pm Jeremy Lohman, Purdue University
Exploring the molecular evolution of acyltransferase-less polyketide synthase ketosynthase domains
2:00 pm Jordan Baumhardt, Illinois State University
A novel method for analyzing the reversible inhibition of an enzyme
2:30 am Rui Wu, Loyola University
The crystal structure of Nitrosomonas europaea sucrose synthase: Insights into the evolutionary origin of sucrose metabolism in prokaryotes
3:00 pm Alexander Statsyuk, Northwestern University
Chemical tools to study E3 ubiquitin ligases
3:30 pm Closing remarks
Local Arrangements Chair: Rick Silverman, Northwestern University
3:35 pm (optional) Max Funk, National Science Foundation (LR2 Tech Building)
Funding opportunities through the National Science Foundation Chemistry of Life Processes Program
4:00 pm Poster session with graduate student and postdoc poster competitions
Halls of the Technology Institute Building
4:15 pm Poster judging begins
6:15 pm Poster prizes awarded
6:30 pm End